Key Clinical Results 

Study comparison: PMD Pro + PMD Total Solution Cream versus PMD Total Solution Cream alone.

• Skin Gloss: Increased by 21.34% in the combination group compared with 10.68% in the cream-only group (p = 0.029).
• Inner Skin Elasticity: Increased by 10.13% in the combination group compared with 2.91% in the cream-only group (p = 0.018).
• Epidermal Hydration: Increased by 6.13% in the combination group compared with 2.35% in the cream-only group (p = 0.031).
• Skin Brightness: Increased by 2.61% in the combination group compared with 1.34% in the cream-only group (reported p < 0.05; verify the exact statistical result against the original report).
  
  

These results represent reported changes from baseline after 28 days of treatment. Individual outcome measures should be interpreted according to their respective measurement methods and statistical comparisons.

Clinical Outcome Assessments

1. Skin Gloss & Surface Radiance

Measurement instrument: Delfin Glossmeter

Clinical objective: To evaluate changes in skin surface gloss following the use of PMD Pro in combination with PMD Total Solution Cream.

Skin gloss was assessed using a glossmeter that measures specular light reflection from the skin's surface. This provides an objective measurement of surface radiance and helps quantify changes in the skin's reflective properties over the treatment period.

Reported findings: At Week 4, skin gloss increased by 21.34% in the combination group compared with 10.68% in the cream-only group (p = 0.029).

2. Inner Skin Elasticity & Dermal Firmness

Measurement instrument: Delfin Elastimeter

Clinical objective: To assess changes in the skin's mechanical elasticity following the 28-day treatment protocol.

Skin elasticity was evaluated using an elastimeter to measure the skin's mechanical response to applied force. This assessment provides an instrumental measure of the skin's ability to respond to deformation and recover, supporting the evaluation of changes associated with skin firmness and elasticity.

Reported findings: At Week 4, inner skin elasticity increased by 10.13% in the combination group compared with 2.91% in the cream-only group (p = 0.018).

3. Epidermal Hydration & Stratum Corneum Moisture

Measurement instrument: Corneometer CM 825

Clinical objective: To evaluate changes in epidermal moisture levels following treatment.

The Corneometer CM 825 measures the electrical capacitance of the skin, which is used to assess hydration in the stratum corneum, the outermost layer of the epidermis. Instrumental hydration measurements provide a quantitative way to compare skin moisture levels at baseline and throughout the study.

Reported findings: At Week 4, skin hydration increased by 6.13% in the combination group compared with 2.35% in the cream-only group (p = 0.031).

4. Overall Skin Brightness & Tone Clarity

Measurement instruments: Minolta Spectrophotometer and VISIA-CR imaging system

Clinical objective: To assess changes in skin brightness and the appearance of overall skin tone over the treatment period.

A spectrophotometer measures the skin's optical properties and color characteristics, allowing changes in brightness to be quantified. VISIA-CR imaging provides complementary photographic documentation of skin appearance under controlled imaging conditions. Together, these methods support the evaluation of measurable changes in skin appearance.

Reported findings: At Week 4, the skin brightness index increased by 2.61% in the combination group compared with 1.34% in the cream-only group. The reported statistical significance is p < 0.05; the exact test and outcome-specific p-value should be confirmed against the original report.

Study Design & Population

This was a 28-day, single-center controlled laboratory study evaluating PMD Pro used in combination with PMD Total Solution Cream compared with PMD Total Solution Cream alone. The study included 20 female participants aged 30–55.

Assessments were performed at baseline (Week 0), Week 2 and Week 4 to evaluate changes over the treatment period. The comparison group received the same topical cream without the PMD Pro device, providing a reference for evaluating the observed changes associated with the combination regimen.

Treatment Protocol

Participants in the combination group used PMD Pro according to a prescribed schedule over 28 days:

• Massage Mode: Twice daily, morning and evening.
• Peeling Mode: Once weekly in the evening.
• Topical skincare: PMD Total Solution Cream used alongside the device regimen.

Participants in the comparison group used PMD Total Solution Cream alone. This design allowed investigators to compare outcomes between the combination regimen and topical skincare alone over the same assessment period.

Instrumentation & Measurement Methods

Objective skin assessments were performed using instruments selected for the specific outcome being evaluated:

• Delfin Glossmeter: Measurement of specular reflection to assess surface gloss.
• Delfin Elastimeter: Assessment of the skin's mechanical elasticity.
• Corneometer CM 825: Measurement of electrical capacitance as an indicator of stratum corneum hydration.
• Minolta Spectrophotometer: Instrumental assessment of skin color and brightness characteristics.
• VISIA-CR: Standardized photographic imaging to document skin appearance.
• Participant self-assessment questionnaire: Collection of subjective feedback on perceived skin changes and treatment experience.

The measurement methods were selected to evaluate distinct skin characteristics rather than relying exclusively on subjective assessments.

Statistical Analysis

Statistical analyses were conducted using SPSS version 18.0. Paired and independent t-tests were reported, with statistical significance defined as p < 0.05.

Paired analyses can be used to evaluate changes within a group over time, while independent-group comparisons can assess differences between the combination and cream-only groups. The interpretation of each result depends on the specific test applied, the comparison performed and the associated p-value.

Outcome-specific statistical results should be verified against the original report before publication.

Safety & Participant Feedback

The available study summaries report a skin irritation index of 0.00 and 100% participant satisfaction in the gloss study. These findings should be attributed to the relevant study assessment rather than generalized across all outcomes without confirmation.

The study summaries do not, by themselves, establish the absence of all adverse effects or demonstrate that every measured outcome was statistically significant.

Study Limitations & Interpretation

The reported findings reflect a 28-day study involving 20 female participants aged 30–55 in a single-center laboratory setting. The relatively small study population and short observation period should be considered when interpreting the results.

The findings describe changes observed under the study's specific treatment protocol and measurement conditions. They should not be interpreted as a guarantee of equivalent results for every user or as evidence of long-term outcomes beyond the assessment period.

Key Results

The clinical study summary reports improvements across five skin-quality categories following eight weeks of weekly treatments with PMD's patented microdermabrasion technology.

• Overall Skin Quality: Approximately 70% average improvement.
• Skin Roughness: Approximately 173% improvement.
• Sun Damage: Approximately 80% improvement.
• Acne: Approximately 33% improvement.
• Wrinkles: Approximately 7% improvement.
  
  

The study summary also reports overall improvements ranging from 55% to 75% across evaluated outcomes. Figure 1 documents weekly tracking of these categories over the eight-week treatment period.

Safety Observations 
No adverse results or side effects were reported during the treatment and observation period.

Note: The percentages above are reported in the supplied study summary. The original report should be consulted to verify the measurement methods, calculations, and statistical significance of each outcome.

Study Design & Population

A clinical evaluation examining the effects of PMD's patented microdermabrasion technology on acne, skin roughness, wrinkles, sun damage, and overall skin quality.

• Study population: 54 participants (44 female and 10 male).
• Investigators: C. S. Mass, H. D. Stupak, and B. M. Loos, facial plastic surgeons affiliated with UCSF.
• Treatment period: 8 weeks.
• Follow-up period: 16 additional weeks of observation.
• Treatment frequency: Weekly treatments using PMD's patented microdermabrasion technology.

Treatment Protocol & Evaluation Criteria
Participants received weekly treatments over eight weeks. Outcomes were tracked across five categories: acne, skin roughness, wrinkles, sun damage, and overall skin quality. Figure 1 in the supplied study summary presents the weekly progression of these outcomes.

Physician Conclusions

The investigators concluded that PMD's patented microdermabrasion technology may improve the appearance of brown spots, freckles, skin discoloration, acne scarring, skin roughness, and overall skin quality.

The report also proposes that microdermabrasion may support accelerated skin renewal and resurfacing, with topical agents used alongside the technology potentially enhancing results. These statements reflect the conclusions presented in the supplied study summary.

Participants reportedly found PMD's technology easy to use, convenient, and beneficial to the appearance of their skin. Before-and-after photographs in the study materials document changes between Week 1 and Week 8.

One participant reported improvements in the appearance of dark spots and overall skin health following treatment:

“I have tried several skin lightening products in hopes of bringing back the skin I had 10 years ago before 3 pregnancies, which had created a collage of dark spots on my face. Until now I had no change. My husband, friends and family are amazed at the change and not only have my dark brown spots lightened significantly, but how healthy my skin looks."  

Key Clinical Results

• Fine Lines & Wrinkles: Significant improvements in fine wrinkles reported by the third treatment, with further improvements after six weekly treatments.
• Skin Brightness & Pigmentation: Improvements in dyschromia, actinic changes, dullness and uneven pigmentation across multiple studies.
• Pore Appearance: Significant improvements in the appearance of large pores following repeated treatments.
• Skin Structure & Collagen: Histological studies reported epidermal and papillary dermal thickening, with collagen and elastic fiber deposition following microdermabrasion.
• Long-Term Changes: Some clinical and histological changes persisted after a 90-day period without treatment.
• Topical Ingredient Delivery: Experimental research reported up to 20-fold higher vitamin C skin deposition following microdermabrasion under the tested conditions.

Clinical Outcome Assessments

1. Skin Texture, Fine Lines & Photoaging

Study: Spencer JM, Kurtz ES (2006)

Study Design & Population: Six weekly facial microdermabrasion treatments in 16 women, alongside a cleanser and lotion skincare regimen.

Key Findings: Fine wrinkles, dullness, pigmentation and large pores significantly improved by the third treatment, with further improvement by the sixth treatment. Colorimetry measurements showed increased skin brightness and decreased yellowness.

2. Skin Tone & Long-Term Histological Changes

Study: Freedman BM, Rueda-Pedraza E, Earley RV (2002)

Study Design & Population: Eleven volunteers aged 31–62 received six aluminum oxide microdermabrasion treatments spaced 7–10 days apart. Clinical photography and skin biopsies were conducted before treatment, after three and six treatments, and following a 90-day no-treatment period.

Key Findings: Clinical improvements in dyschromia, actinic changes and fine lines were observed after six treatments. Histological analysis showed epidermal thickening, papillary dermal thickening, and collagen and elastic fiber deposition. Some changes persisted after 90 days without treatment, although they diminished from post-treatment levels.

3. Skin Discoloration & Collagen Organization

Study: A Prospective Controlled Assessment of Microdermabrasion for Damaged Skin and Fine Rhytides (2004)

Study Design & Population: Seventeen participants completed the study, according to the supplied summary.

Key Findings: Significant improvement in hyperchromic discoloration was reported. Histological analysis of matched punch biopsies also showed increased organized collagen in treated versus untreated sites.

4. Skin Permeability & Topical Ingredient Delivery

Study: Gill HS, Andrews SN, Sakthivel SK, et al. (2009)

Study Objective: To evaluate how microdermabrasion conditions affect skin tissue removal and permeability.

Key Findings: Moderate microdermabrasion conditions selectively removed the full thickness of the stratum corneum while causing little damage to deeper tissues. Experimental testing also demonstrated increased skin permeability and delivery of a model fluorescent compound.

Separate vitamin C research reported approximately 20-fold higher skin deposition following microdermabrasion under the specific experimental conditions tested. This finding should not be generalized to all topical ingredients or at-home devices.

Study Methods & Measurement

The cited research used a combination of clinical photography, ultraviolet fluorescence photography, skin biopsies, colorimetry and histological analysis to assess visible skin changes, pigmentation patterns and structural changes within the epidermis and dermis.

Experimental permeability studies additionally evaluated tissue removal and the delivery of topical compounds through treated skin.

Clinical Interpretation

Collectively, these studies suggest that microdermabrasion may improve the appearance of fine lines, uneven pigmentation, dullness and skin texture. Histological and experimental findings also provide evidence of changes in skin structure and permeability under specific treatment conditions.

Results vary according to treatment intensity, frequency, study population and methodology. Findings from clinical and laboratory studies should not be assumed to represent identical outcomes with every microdermabrasion device.

Key Results

• 100% reported smoother, softer skin after their first use.
• 96% noticed improved absorption of their skincare products after using PMD Personal Microderm.
  Panel Overview

In 2016, 30 women were selected to use PMD Personal Microderm over an eight-week period and provide feedback about their experience.

Consumer-Reported Outcomes

Skin Smoothness & Softness
All participants (100%) reported that their skin felt smoother and softer after their first use.

Skincare Product Absorption
Most participants (96%) reported that their skincare products absorbed better after using the device.

Study Notes

These findings reflect participant-reported experiences and perceptions. They are not equivalent to instrument-measured clinical outcomes or evidence of statistical significance.